1U3H
Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002250 | biological_process | adaptive immune response |
| A | 0002376 | biological_process | immune system process |
| A | 0042101 | cellular_component | T cell receptor complex |
| B | 0002250 | biological_process | adaptive immune response |
| B | 0002376 | biological_process | immune system process |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007166 | biological_process | cell surface receptor signaling pathway |
| B | 0042101 | cellular_component | T cell receptor complex |
| C | 0006955 | biological_process | immune response |
| C | 0016020 | cellular_component | membrane |
| C | 0019882 | biological_process | antigen processing and presentation |
| C | 0042613 | cellular_component | MHC class II protein complex |
| D | 0006955 | biological_process | immune response |
| D | 0016020 | cellular_component | membrane |
| D | 0019882 | biological_process | antigen processing and presentation |
| D | 0042613 | cellular_component | MHC class II protein complex |
| E | 0002250 | biological_process | adaptive immune response |
| E | 0002376 | biological_process | immune system process |
| E | 0042101 | cellular_component | T cell receptor complex |
| F | 0002250 | biological_process | adaptive immune response |
| F | 0002376 | biological_process | immune system process |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0007166 | biological_process | cell surface receptor signaling pathway |
| F | 0042101 | cellular_component | T cell receptor complex |
| G | 0006955 | biological_process | immune response |
| G | 0016020 | cellular_component | membrane |
| G | 0019882 | biological_process | antigen processing and presentation |
| G | 0042613 | cellular_component | MHC class II protein complex |
| H | 0006955 | biological_process | immune response |
| H | 0016020 | cellular_component | membrane |
| H | 0019882 | biological_process | antigen processing and presentation |
| H | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVEH |
| Chain | Residue | Details |
| D | TYR171-HIS177 | |
| C | TYR161-HIS167 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"D segment"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 360 |
| Details | Domain: {"description":"Ig-like C1-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 162 |
| Details | Region: {"description":"Alpha-1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 186 |
| Details | Region: {"description":"Alpha-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 184 |
| Details | Region: {"description":"Beta-1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 186 |
| Details | Region: {"description":"Beta-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02687","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16452087","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
