1U0M
Crystal Structure of 1,3,6,8-Tetrahydroxynaphthalene Synthase (THNS) from Streptomyces coelicolor A3(2): a Bacterial Type III Polyketide Synthase (PKS) Provides Insights into Enzymatic Control of Reactive Polyketide Intermediates
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | putative polyketide synthase | polymer | 382 | 41669.3 | 2 | UniProt (Q9FCA7) Pfam (PF00195) Pfam (PF02797) In PDB | Streptomyces coelicolor | |
| 2 | A, B | POLYETHYLENE GLYCOL (N=34) | non-polymer | 1529.8 | 2 | Chemie (15P) | |||
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 374 (UniProt: Q9FCA7)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | cloning artifact |
| Ser -6 | - | cloning artifact |
| His -5 | - | cloning artifact |
| Gly -4 | - | cloning artifact |
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Gly -1 | - | cloning artifact |
| Phe 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83338.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3243.8 | |
| All* | Total formula weight | 86582.5 |
