1TZD
CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Inositol-trisphosphate 3-kinase A | polymer | 275 | 31791.1 | 2 | UniProt (P17105) Pfam (PF03770) In PDB | Rattus norvegicus (Norway rat) | Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A, IP3 3-kinase A |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 185 - 459 (UniProt: P17105)
| PDB | External Database | Details |
|---|---|---|
| Mse 217 | Leu 217 | engineered mutation |
| Asn 423 | Asp 423 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63582.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 878.7 | |
| All* | Total formula weight | 64460.9 |
