1TSQ

CRYSTAL STRUCTURE OF AP2V SUBSTRATE VARIANT OF NC-P1 DECAMER PEPTIDE IN COMPLEX WITH V82A/D25N HIV-1 PROTEASE MUTANT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Pol polyprotein	polymer	99	10772.7	2	UniProt (P03369) Pfam (PF00077) In PDB
2	P	AP2V NC-P1 SUBSTRATE PEPTIDE	polymer	10	1190.4	1	UniProt (P04591) In PDB
3	A, B	ACETATE ION	non-polymer		59.0	10	Chemie (ACT)
4		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A, B: 1 - 99 (UniProt: P03369)

PDB	External Database	Details
Lys 7	Gln 63	engineered mutation
Asn 25	Asp 81	engineered mutation
Ala 82	Val 138	engineered mutation

P: 2 - 11 (UniProt: P04591)

PDB	External Database	Details
Val 4	Ala 430	see remark 999
Asn 11	Trp 437	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	22735.8
Non-Polymers*	Number of molecules	10
	Total formula weight	590.4
All*	Total formula weight	23326.3

*Water molecules are not included.