1TPZ
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | interferon-inducible GTPase | polymer | 422 | 48722.9 | 2 | UniProt (Q9QZ85) Pfam (PF05049) | Mus musculus (house mouse) | IIGP1 |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 3 | D, F (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H (B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 589 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 411 (UniProt: Q9QZ85)
| PDB | External Database | Details |
|---|---|---|
| Lys 412 | - | cloning artifact |
| Leu 413 | - | cloning artifact |
| Gly 414 | - | cloning artifact |
| Arg 415 | - | cloning artifact |
| Leu 416 | - | cloning artifact |
| Glu 417 | - | cloning artifact |
| Arg 418 | - | cloning artifact |
| Pro 419 | - | cloning artifact |
| His 420 | - | cloning artifact |
| Arg 421 | - | cloning artifact |
| Asp 422 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97445.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1115.3 | |
| All* | Total formula weight | 98561.0 |
