1TG2
Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phenylalanine-4-hydroxylase | polymer | 308 | 35730.5 | 1 | UniProt (P00439) Pfam (PF00351) In PDB | Homo sapiens (human) | PAH, Phe-4- monooxygenase |
| 2 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 3 | A | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE | non-polymer | 239.2 | 1 | Chemie (H2B) | |||
| 4 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A: 117 - 424 (UniProt: P00439)
| PDB | External Database | Details |
|---|---|---|
| Thr 313 | Ala 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35730.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 295.1 | |
| All* | Total formula weight | 36025.6 |
