1TB7
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With AMP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 332 | 38207.3 | 2 | UniProt (Q08499) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE3, PDE43 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
5 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 27 | Chemie (EDO) | |||
6 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
7 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 86 - 413 (UniProt: Q08499)
PDB | External Database | Details |
---|---|---|
Gly 82 | - | expression tag |
Ser 83 | - | expression tag |
His 84 | - | expression tag |
Met 85 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 76414.5 | |
Non-Polymers* | Number of molecules | 34 |
Total formula weight | 2832.0 | |
All* | Total formula weight | 79246.6 |