1TB7
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 332 | 38207.3 | 2 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | C, U (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, V (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, W (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 5 | AA, BA, CA, DA, EA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 27 | Chemie (EDO) | |||
| 6 | T (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 7 | KA, LA (A, B) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 86 - 413 (UniProt: Q08499)
| PDB | External Database | Details |
|---|---|---|
| Gly 82 | - | expression tag |
| Ser 83 | - | expression tag |
| His 84 | - | expression tag |
| Met 85 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76414.5 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 2832.0 | |
| All* | Total formula weight | 79246.6 |
