1T74
Crystal structure of the androgen receptor ligand binding domain in complex with a WxxLF motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Androgen receptor | polymer | 269 | 30878.0 | 1 | UniProt (O97775) Pfam (PF00104) In PDB | Pan troglodytes (chimpanzee) | Dihydrotestosterone receptor |
| 2 | B | WxxLF motif peptide | polymer | 15 | 1756.8 | 1 | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 662 - 919 (UniProt: O97775)
| PDB | External Database | Details |
|---|---|---|
| Gly 651 | - | cloning artifact |
| Ser 652 | - | cloning artifact |
| Pro 653 | - | cloning artifact |
| Gly 654 | - | cloning artifact |
| Ile 655 | - | cloning artifact |
| Ser 656 | - | cloning artifact |
| Gly 657 | - | cloning artifact |
| Gly 658 | - | cloning artifact |
| Gly 659 | - | cloning artifact |
| Gly 660 | - | cloning artifact |
| Gly 661 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32634.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 448.6 | |
| All* | Total formula weight | 33083.4 |
