1T6B
Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Protective Antigen | polymer | 735 | 82768.8 | 1 | UniProt (P13423) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) Pfam (PF20835) | Bacillus anthracis | |
| 2 | B (Y) | Anthrax toxin receptor 2 | polymer | 189 | 20630.6 | 1 | UniProt (P58335) Pfam (PF00092) | Homo sapiens (human) | Capillary morphogenesis protein-2; CMG-2 |
| 3 | C, D (X) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E, F (X) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | G (X) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | H (Y) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 7 | I, J (X, Y) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
Y: 35 - 212 (UniProt: P58335)
| PDB | External Database | Details |
|---|---|---|
| Gly 30 | - | cloning artifact |
| Ser 31 | - | cloning artifact |
| His 32 | - | cloning artifact |
| Met 33 | - | cloning artifact |
| Leu 34 | - | cloning artifact |
| Asp 36 | Gln 36 | cloning artifact |
| Arg 38 | Ser 38 | cloning artifact |
| Gly 39 | Cys 39 | cloning artifact |
| Ser 213 | - | cloning artifact |
| Asn 214 | - | cloning artifact |
| Gly 215 | - | cloning artifact |
| Ile 216 | - | cloning artifact |
| Ala 217 | - | cloning artifact |
| Ala 218 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 103399.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 375.3 | |
| All* | Total formula weight | 103774.7 |
