1T65
Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 251 | 29277.3 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | Homo sapiens (human) | NCoA-2, Transcriptional intermediary factor 2 |
| 3 | C (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30857.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 290.4 | |
| All* | Total formula weight | 31147.6 |
