1T5Z
Crystal Structure of the Androgen Receptor Ligand Binding Domain (LBD) with DHT and a peptide derived from its physiological coactivator ARA70
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 251 | 29277.3 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor |
| 2 | B (B) | Nuclear receptor coactivator 4 | polymer | 15 | 1893.1 | 1 | UniProt (Q13772) | Homo sapiens (human) | NCoA-4, 70 kDa androgen receptor coactivator, 70 kDa AR-activator, Ret-activating protein ELE1 |
| 3 | C (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) PubChem (16395945) PubChem (1779160) PubChem (15) PubChem (23729584) PubChem (10635) PubChem (44264584) PubChem (44307156) PubChem (44308180) PubChem (44314545) PubChem (147320) PubChem (1779165) PubChem (54132599) PubChem (1779163) PubChem (44403751) PubChem (67080676) PubChem (68213431) PubChem (70627790) PubChem (57253355) PubChem (667503) PubChem (76333143) PubChem (2748143) PubChem (928651) PubChem (11302) PubChem (90350225) PubChem (968803) PubChem (6951009) PubChem (124916763) PubChem (6432518) PubChem (133612463) PubChem (7052570) PubChem (7052571) PubChem (11869360) PubChem (9965809) PubChem (10379482) PubChem (10902374) PubChem (124305346) PubChem (124335861) PubChem (124350819) PubChem (124362930) PubChem (124402106) PubChem (124420348) PubChem (11860392) PubChem (11867857) PubChem (11867858) PubChem (11867859) PubChem (11867860) PubChem (11869358) PubChem (11869359) PubChem (11869361) PubChem (11914201) PubChem (11920866) PubChem (12446746) PubChem (12446747) PubChem (12446748) PubChem (12446749) PubChem (12446752) PubChem (124907326) PubChem (124907327) PubChem (16111632) PubChem (134753818) PubChem (139564330) PubChem (141909893) PubChem (142776876) PubChem (145087815) PubChem (156740897) PubChem (162854571) PubChem (162854572) PubChem (162854573) PubChem (164663566) PubChem (165146196) PubChem (165431280) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31170.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 290.4 | |
| All* | Total formula weight | 31460.9 |
