1T4F
Structure of human MDM2 in complex with an optimized p53 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | M | Ubiquitin-protein ligase E3 Mdm2 | polymer | 110 | 12592.4 | 1 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (human) | p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2 |
2 | P | optimized p53 peptide | polymer | 9 | 1217.4 | 1 | |||
3 | M | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
M: 17 - 125 (UniProt: Q00987)
PDB | External Database | Details |
---|---|---|
Gly 16 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13809.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 96.1 | |
All* | Total formula weight | 13905.8 |