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1T32

A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cathepsin Gpolymer22425484.21UniProt (P08311)
Pfam (PF00089)
Homo sapiens (human)CG
2B, C, D, E, F
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
3G
(A)
2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACIDnon-polymer670.71Chemie (OHH)
4H
(A)
waterwater18.0261Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight25484.2
Non-Polymers*Number of molecules6
Total formula weight1151.0
All*Total formula weight26635.2
*Water molecules are not included.

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PDB entries from 2025-12-17

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