1T2F
Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | L-lactate dehydrogenase B chain | polymer | 333 | 36580.3 | 4 | UniProt (P07195) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (human) | LDH-B, LDH heart subunit, LDH-H |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID | non-polymer | 130.1 | 4 | Chemie (OXQ) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 333 (UniProt: P07195)
| PDB | External Database | Details |
|---|---|---|
| Phe 332 | Asp 332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146321.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3173.9 | |
| All* | Total formula weight | 149495.1 |
