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1T09

Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isocitrate dehydrogenase [NADP] cytoplasmicpolymer41446720.22UniProt (O75874)
Pfam (PF00180)
Homo sapiens (human)cytosolic NADP(+)-dependent isocitrate dehydrogenase, Oxalosuccinate decarboxylase, IDH, NADP+-specific ICDH, IDP
2C, D
(A, B)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
PubChem (5885)
PubChem (46936685)
PubChem (71717786)
PubChem (4412)
PubChem (90473931)
PubChem (91972139)
PubChem (145946263)
PubChem (153311489)
PubChem (174001641)
PubChem (165382010)
3E, F
(A, B)
waterwater18.0155Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight93440.4
Non-Polymers*Number of molecules2
Total formula weight1486.8
All*Total formula weight94927.3
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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