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1T09

Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isocitrate dehydrogenase [NADP] cytoplasmicpolymer41446720.22UniProt (O75874)
Pfam (PF00180)
Homo sapiens (human)cytosolic NADP(+)-dependent isocitrate dehydrogenase, Oxalosuccinate decarboxylase, IDH, NADP+-specific ICDH, IDP
2C, D
(A, B)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
3E, F
(A, B)
waterwater18.0155Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight93440.4
Non-Polymers*Number of molecules2
Total formula weight1486.8
All*Total formula weight94927.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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