1T09

Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Isocitrate dehydrogenase [NADP] cytoplasmic	polymer	414	46720.2	2	UniProt (O75874) Pfam (PF00180) In PDB	Homo sapiens (human)	cytosolic NADP(+)-dependent isocitrate dehydrogenase, Oxalosuccinate decarboxylase, IDH, NADP+-specific ICDH, IDP
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3		water	water		18.0	155	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93440.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1486.8
All*	Total formula weight	94927.3

*Water molecules are not included.