1SSG
Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Triosephosphate isomerase | polymer | 247 | 26588.3 | 2 | UniProt (P00940) Pfam (PF00121) | Gallus gallus (chicken) | TIM |
| 2 | C, G (A, B) | 2-PHOSPHOGLYCOLIC ACID | non-polymer | 156.0 | 2 | Chemie (PGA) | |||
| 3 | D, E, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | F, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 248 (UniProt: P00940)
| PDB | External Database | Details |
|---|---|---|
| Tyr 174 | Lys 173 | engineered mutation |
| Ser 175 | Thr 174 | engineered mutation |
| Leu 176 | Ala 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53176.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 972.6 | |
| All* | Total formula weight | 54149.2 |
