1SR9

Crystal Structure of LeuA from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	2-isopropylmalate synthase	polymer	644	70750.2	2	UniProt (P96420) Pfam (PF00682) Pfam (PF08502) UniProt (by SIFTS) (P9WQB3) In PDB	Mycobacterium tuberculosis	Alpha-isopropylmalate synthase, LeuA, Alpha-IPM synthetase
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	A, B	3-METHYL-2-OXOBUTANOIC ACID	non-polymer		116.1	2	Chemie (KIV)
5		water	water		18.0	466	Chemie (HOH)

Sequence modifications

A, B: 1 - 644 (UniProt: P96420)

PDB	External Database	Details
Mse 1	Met 1	MODIFIED RESIDUE
Mse 41	Met 41	MODIFIED RESIDUE
Mse 90	Met 90	MODIFIED RESIDUE
Mse 98	Met 98	MODIFIED RESIDUE
Mse 105	Met 105	MODIFIED RESIDUE
Mse 257	Met 257	MODIFIED RESIDUE
Mse 270	Met 270	MODIFIED RESIDUE
Mse 390	Met 390	MODIFIED RESIDUE
Mse 404	Met 404	MODIFIED RESIDUE
Mse 441	Met 441	MODIFIED RESIDUE
Mse 480	Met 480	MODIFIED RESIDUE
Mse 559	Met 559	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	141500.3
Non-Polymers*	Number of molecules	5
	Total formula weight	398.5
All*	Total formula weight	141898.8

*Water molecules are not included.