1SP4
Crystal structure of NS-134 in complex with bovine cathepsin B: a two headed epoxysuccinyl inhibitor extends along the whole active site cleft
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cathepsin B | polymer | 48 | 5300.9 | 1 | UniProt (P07688) In PDB | Bos taurus (cattle) | |
| 2 | B | Cathepsin B | polymer | 205 | 22233.7 | 1 | UniProt (P07688) Pfam (PF00112) In PDB | Bos taurus (cattle) | |
| 3 | B | methyl N-[(2S)-4-{[(1S)-1-{[(2S)-2-carboxypyrrolidin-1-yl]carbonyl}-3-methylbutyl]amino}-2-hydroxy-4-oxobutanoyl]-L-leucylglycylglycinate | non-polymer | 583.6 | 1 | BIRD (PRD_000444) Chemie (EP2) | |||
| 4 | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27534.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 583.6 | |
| All* | Total formula weight | 28118.2 |
