1SO2
CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B In COMPLEX WITH A DIHYDROPYRIDAZINE INHIBITOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | polymer | 420 | 48158.8 | 4 | UniProt (Q13370) Pfam (PF00233) In PDB | Homo sapiens (human) | Cyclic GMP inhibited phosphodiesterase B, CGI-PDE B, CGIPDE1, CGIP1 |
2 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
3 | A, B | 1-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL | non-polymer | 365.5 | 4 | Chemie (HG9) | |||
4 | A, B, C, D | 6-(4-{[2-(3-IODOBENZYL)-3-OXOCYCLOHEX-1-EN-1-YL]AMINO}PHENYL)-5-METHYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE | non-polymer | 513.4 | 4 | Chemie (666) | |||
5 | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 192635.1 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 3734.1 | |
All* | Total formula weight | 196369.2 |