1SMC
Mycobacterium tuberculosis dUTPase complexed with dUTP in the absence of metal ion.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Deoxyuridine 5'-triphosphate nucleotidohydrolase | polymer | 174 | 17992.3 | 3 | UniProt (P0A552) Pfam (PF00692) UniProt (by SIFTS) (P9WNS5) | Mycobacterium tuberculosis | dUTPase, dUTP pyrophosphatase |
| 2 | D, H, I (A, C) | DEOXYURIDINE-5'-TRIPHOSPHATE | non-polymer | 468.1 | 3 | Chemie (DUT) | |||
| 3 | E, F, J (A, B, C) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 3 | Chemie (TRS) | |||
| 4 | G (C) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | K, L, M (A, B, C) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 154 (UniProt: P0A552)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53976.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1832.9 | |
| All* | Total formula weight | 55809.8 |
