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1SM2

Crystal structure of the phosphorylated Interleukin-2 tyrosine kinase catalytic domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tyrosine-protein kinase ITK/TSKpolymer26430104.42UniProt (Q08881)
Pfam (PF07714)
Homo sapiens (human)T-cell-specific kinase, Tyrosine-protein kinase Lyk, Kinase EMT
2C, D
(A, B)
STAUROSPORINEnon-polymer466.52Chemie (STU)
3E, F
(A, B)
waterwater18.0251Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60208.8
Non-Polymers*Number of molecules2
Total formula weight933.1
All*Total formula weight61141.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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