1SKW

Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	P	5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3'	polymer	21	6426.2	1
2	T	5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'	polymer	25	7922.1	1
3	A	DNA polymerase	polymer	698	79089.8	1	UniProt (P00581) Pfam (PF00476) In PDB	Enterobacteria phage T7	T7 DNA polymerase
4	B	thioredoxin 1	polymer	108	11687.4	1	UniProt (P0AA25) Pfam (PF00085) In PDB	Escherichia coli
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6		water	water		18.0	201	Chemie (HOH)

Sequence modifications

A: 1 - 704 (UniProt: P00581)

PDB	External Database	Details
-	Lys 118	deletion
-	Arg 119	deletion
-	Phe 120	deletion
-	Gly 121	deletion
-	Ser 122	deletion
-	His 123	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	105125.4
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	105149.7

*Water molecules are not included.