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1SJ0

Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Estrogen receptorpolymer24828316.31UniProt (P03372)
Pfam (PF00104)
Homo sapiens (human)ER, Estradiol receptor, ER-alpha
2B
(A)
(2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OLnon-polymer463.61Chemie (E4D)
3C
(A)
waterwater18.0152Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28316.3
Non-Polymers*Number of molecules1
Total formula weight463.6
All*Total formula weight28779.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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