1SHY
The Crystal Structure of HGF beta-chain in Complex with the Sema Domain of the Met Receptor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hepatocyte growth factor | polymer | 234 | 26014.1 | 1 | UniProt (P14210) Pfam (PF00089) In PDB | Homo sapiens (human) | Scatter factor, SF, Hepatopoeitin A |
2 | B | Hepatocyte growth factor receptor | polymer | 551 | 62535.9 | 1 | UniProt (P08581) Pfam (PF01403) Pfam (PF01437) In PDB | Homo sapiens (human) | Met proto-oncogene tyrosine kinase, c-met, HGF receptor, HGF-SF receptor |
Sequence modifications
A: 495 - 728 (UniProt: P14210)
B: 25 - 567 (UniProt: P08581)
PDB | External Database | Details |
---|---|---|
Ser 604 | Cys 604 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Leu 303 | Lys 303 | SEE REMARK 999 |
Val 304 | Arg 304 | SEE REMARK 999 |
Pro 305 | Lys 305 | SEE REMARK 999 |
Arg 306 | Lys 306 | SEE REMARK 999 |
Gly 307 | Arg 307 | SEE REMARK 999 |
His 568 | - | expression tag |
His 569 | - | expression tag |
His 570 | - | expression tag |
His 571 | - | expression tag |
His 572 | - | expression tag |
His 573 | - | expression tag |
His 574 | - | expression tag |
His 575 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 88550.0 | |
All* | Total formula weight | 88550.0 |