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1SG1

Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Beta-nerve growth factorpolymer12013515.42UniProt (P01138)
Pfam (PF00243)
Homo sapiens (human)Beta-NGF
2C
(X)
Tumor necrosis factor receptor superfamily member 16polymer16117258.01UniProt (P07174)
Pfam (PF00020)
Rattus norvegicus (Norway rat)Low- affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR
3D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4E, F, G
(A, B, X)
waterwater18.0375Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44288.8
Non-Polymers*Number of molecules1
Total formula weight35.5
All*Total formula weight44324.3
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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