1SEG
Crystal structure of a toxin chimera between Lqh-alpha-IT from the scorpion Leiurus quinquestriatus hebraeus and AAH2 from Androctonus australis hector
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | AAH2: LQH-ALPHA-IT (FACE) CHIMERIC TOXIN | polymer | 64 | 7423.5 | 1 | UniProt (P01484) Pfam (PF00537) In PDB | Androctonus australis hector | AaH II, AaHII, AaH2 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 4 | A | PROPANOIC ACID | non-polymer | 74.1 | 1 | Chemie (PPI) | |||
| 5 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 1 - 64 (UniProt: P01484)
| PDB | External Database | Details |
|---|---|---|
| Lys 8 | Asp 27 | engineered mutation |
| Asn 9 | Asp 28 | engineered mutation |
| Tyr 10 | Val 29 | engineered mutation |
| Phe 17 | Gly 36 | engineered mutation |
| Pro 56 | Arg 75 | engineered mutation |
| Ile 57 | Thr 76 | engineered mutation |
| Arg 58 | Lys 77 | engineered mutation |
| Val 59 | Gly 78 | engineered mutation |
| Lys 62 | Arg 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 7423.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 294.2 | |
| All* | Total formula weight | 7717.6 |
