1SC6
Crystal Structure of W139G D-3-Phosphoglycerate dehydrogenase complexed with NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | D-3-phosphoglycerate dehydrogenase | polymer | 404 | 43713.6 | 4 | UniProt (P0A9T0) Pfam (PF00389) Pfam (PF02826) Pfam (PF22629) | Escherichia coli | PGDH |
| 2 | E, F, G, H (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 7 - 410 (UniProt: P0A9T0)
| PDB | External Database | Details |
|---|---|---|
| Ala 81 | Cys 80 | engineered mutation |
| Ala 83 | Cys 82 | engineered mutation |
| Gly 139 | Trp 138 | engineered mutation |
| Mse 175 | Met 174 | modified residue |
| Mse 203 | Met 202 | modified residue |
| Mse 220 | Met 219 | modified residue |
| Mse 221 | Met 220 | modified residue |
| Mse 229 | Met 228 | modified residue |
| Ala 250 | Cys 249 | engineered mutation |
| Ala 282 | Cys 281 | engineered mutation |
| Mse 341 | Met 340 | modified residue |
| Mse 376 | Met 375 | modified residue |
| Mse 397 | Met 396 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174854.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2653.7 | |
| All* | Total formula weight | 177507.9 |
