1SA1
Tubulin-podophyllotoxin: stathmin-like domain complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha chain | polymer | 451 | 50163.3 | 2 | UniProt (P02550) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (Q2HJ86) | Bos taurus (cattle) | |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 445 | 49907.8 | 2 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (Q6B856) | Bos taurus (cattle) | |
| 3 | E (E) | Stathmin 4 | polymer | 142 | 16713.0 | 1 | UniProt (P02554) Pfam (PF00836) UniProt (by SIFTS) (P63043) | Rattus norvegicus (Norway rat) | Stathmin-like protein B3, RB3 |
| 4 | F, J (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, K (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, L (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 7 | I, M (B, D) | 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE | non-polymer | 414.4 | 2 | Chemie (POD) |
Sequence modifications
A, C: 1 - 451 (UniProt: P02550)
E: 5 - 145 (UniProt: P02554)
| PDB | External Database | Details |
|---|---|---|
| Ile 265 | Ala 265 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Ala 4 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 216855.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2810.2 | |
| All* | Total formula weight | 219665.4 |
