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1S8F

Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ras-related protein Rab-9Apolymer17720037.42UniProt (P24408)
Pfam (PF00071)
Canis lupus familiaris (dog)Rab-9, RAB9 GTPASE
2C, I
(A, B)
STRONTIUM IONnon-polymer87.62Chemie (SR)
PubChem (104798)
3D, K
(A, B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
4E, F, G, L
(A, B)
BENZOIC ACIDnon-polymer122.14Chemie (BEZ)
5H
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
6J
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
PubChem (312)
7M, N
(A, B)
waterwater18.0231Chemie (HOH)
Sequence modifications
A, B: 1000 - 1174 (UniProt: P24408)
PDBExternal DatabaseDetails
Gly 999-cloning artifact
Ala 1000-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40074.8
Non-Polymers*Number of molecules10
Total formula weight1609.9
All*Total formula weight41684.7
*Water molecules are not included.

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PDB entries from 2026-04-01

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