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1S8F

Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ras-related protein Rab-9Apolymer17720037.42UniProt (P24408)
Pfam (PF00071)
Canis lupus familiaris (dog)Rab-9, RAB9 GTPASE
2C, I
(A, B)
STRONTIUM IONnon-polymer87.62Chemie (SR)
3D, K
(A, B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
4E, F, G, L
(A, B)
BENZOIC ACIDnon-polymer122.14Chemie (BEZ)
5H
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6J
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
7M, N
(A, B)
waterwater18.0231Chemie (HOH)
Sequence modifications
A, B: 1000 - 1174 (UniProt: P24408)
PDBExternal DatabaseDetails
Gly 999-cloning artifact
Ala 1000-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40074.8
Non-Polymers*Number of molecules10
Total formula weight1609.9
All*Total formula weight41684.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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