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1S4O

Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p: binary complex with GDP/Mn

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glycolipid 2-alpha-mannosyltransferasepolymer34841349.22UniProt (P27809)
Pfam (PF01793)
Saccharomyces cerevisiae (baker's yeast)Alpha-1,2-mannosyltransferase
2C
(C)
alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1397.21In PDB
GlyTouCan (G83314WY)
3D
(D)
2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G07375KG)
4E, J
(A, B)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
5F, I, K, L
(A, B)
CHLORIDE IONnon-polymer35.54Chemie (CL)
6G, M
(A, B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.22Chemie (GDP)
7H, N
(A, B)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.32Chemie (EPE)
8O, P
(A, B)
waterwater18.0561Chemie (HOH)
Sequence modifications
A, B: 97 - 442 (UniProt: P27809)
PDBExternal DatabaseDetails
Glu 95-cloning artifact
Phe 96-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82698.4
BranchedNumber of molecules2
Total formula weight1821.6
Non-Polymers*Number of molecules10
Total formula weight1614.7
All*Total formula weight86134.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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