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1S3X

The crystal structure of the human Hsp70 ATPase domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Heat shock 70 kDa protein 1polymer38242098.71UniProt (P08107)
Pfam (PF00012)
UniProt (by SIFTS) (P0DMV8)
Homo sapiens (human)HSP70.1, HSP70-1/HSP70-2
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3C, D
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
4E, F
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
5G
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
6H
(A)
waterwater18.0408Chemie (HOH)
Sequence modifications
A: 1 - 382 (UniProt: P08107)
PDBExternal DatabaseDetails
Ile 18Val 18engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42098.7
Non-Polymers*Number of molecules6
Total formula weight648.3
All*Total formula weight42747.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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