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1RX7

STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DIHYDROFOLATE REDUCTASEpolymer15918020.31UniProt (P0ABQ4)
Pfam (PF00186)
Escherichia coliDHFR
2B
(A)
FOLIC ACIDnon-polymer441.41Chemie (FOL)
3C
(A)
waterwater18.023Chemie (HOH)
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
PDBExternal DatabaseDetails
Asp 37Asn 37conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18020.3
Non-Polymers*Number of molecules1
Total formula weight441.4
All*Total formula weight18461.7
*Water molecules are not included.

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PDB entries from 2025-12-10

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