1RT3
AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 REVERSE TRANSCRIPTASE | polymer | 560 | 64667.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | |
| 2 | B (B) | HIV-1 REVERSE TRANSCRIPTASE | polymer | 440 | 51426.1 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | |
| 3 | C (A) | 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE | non-polymer | 298.3 | 1 | Chemie (U05) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Asn 67 | Asp 222 | engineered mutation |
| Arg 70 | Lys 225 | engineered mutation |
| Phe 215 | Thr 370 | engineered mutation |
| Gln 219 | Lys 374 | engineered mutation |
| Csd 280 | Cys 435 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Asn 67 | Asp 131 | engineered mutation |
| Arg 70 | Lys 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116093.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 298.3 | |
| All* | Total formula weight | 116391.4 |
