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1RQD

deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form with the inhibitor GC7 bound in the active site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDeoxyhypusine synthasepolymer36941012.42UniProt (P49366)
Pfam (PF01916)
In PDB
Homo sapiens (human)DHS
2A, BNICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
3A, B1-GUANIDINIUM-7-AMINOHEPTANEnon-polymer174.32Chemie (GC7)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82024.9
Non-Polymers*Number of molecules4
Total formula weight1675.4
All*Total formula weight83700.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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