1RP4

Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hypothetical 65.0 kDa protein in COX14-COS3 intergenic region precursor	polymer	389	45179.7	1	UniProt (Q03103) Pfam (PF04137)	Saccharomyces cerevisiae (baker's yeast)
2	B, C (A)	CADMIUM ION	non-polymer		112.4	2	Chemie (CD)
3	D (A)	1-ETHYL-PYRROLIDINE-2,5-DIONE	non-polymer		127.1	1	Chemie (NEN)
4	E (A)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	1	Chemie (FAD)
5	F (A)	water	water		18.0	102	Chemie (HOH)

Sequence modifications

A: 56 - 424 (UniProt: Q03103)

PDB	External Database	Details
Gly 39	-	cloning artifact
Ser 40	-	cloning artifact
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag
His 44	-	expression tag
His 45	-	expression tag
His 46	-	expression tag
Ser 47	-	cloning artifact
Ser 48	-	cloning artifact
Gly 49	-	cloning artifact
Leu 50	-	cloning artifact
Val 51	-	cloning artifact
Pro 52	-	cloning artifact
Arg 53	-	cloning artifact
Gly 54	-	cloning artifact
Ser 55	-	cloning artifact
Mse 133	Met 133	modified residue
Mse 258	Met 258	modified residue
Mse 271	Met 271	modified residue
Mse 306	Met 306	modified residue
Mse 347	Met 347	modified residue
Mse 415	Met 415	modified residue
Mse 419	Met 419	modified residue
Leu 425	-	cloning artifact
Glu 426	-	cloning artifact
Arg 427	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45179.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1137.5
All*	Total formula weight	46317.3

*Water molecules are not included.