1RMF

STRUCTURES OF A MONOCLONAL ANTI-ICAM-1 ANTIBODY R6.5 FRAGMENT AT 2.8 ANGSTROMS RESOLUTION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L	IGG2A-KAPPA R6.5 FAB (LIGHT CHAIN)	polymer	219	24068.7	1	PIR (S16112)	Mus musculus (house mouse)
2	H	IGG2A-KAPPA R6.5 FAB (HEAVY CHAIN)	polymer	216	23114.9	1	GenBank (2852989)	Mus musculus (house mouse)
3		water	water		18.0	39	Chemie (HOH)

Sequence modifications

L: 1 - 219 (PIR: S16112)

PDB	External Database	Details
Ser 7	Thr 7	CONFLICT
Asn 36	Thr 36	CONFLICT
His 39	Tyr 39	CONFLICT
Ser 45	Pro 45	CONFLICT
Ala 48	Ser 48	CONFLICT
Leu 51	Pro 51	CONFLICT
Lys 55	Arg 55	CONFLICT
Ser 94	Phe 94	CONFLICT
Ser 96	Gly 96	CONFLICT
Leu 101	Tyr 101	CONFLICT
Lys 108	Arg 108	CONFLICT

H: 2 - 213 (GenBank: 2852989)

PDB	External Database	Details
Gln 6	Glu 5	CONFLICT
Ile 30	Thr 29	CONFLICT
Ala 33	Pro 32	CONFLICT
Ile 34	Met 33	CONFLICT
Glu 39	Gln 38	CONFLICT
Ala 53	Thr 52	CONFLICT
Ser 55	Tyr 54	CONFLICT
Asp 57	Asn 56	CONFLICT
Gln 62	Arg 61	CONFLICT
Lys 63	Asn 62	CONFLICT
Asn 77	Ser 76	CONFLICT
Leu 81	Met 80	CONFLICT
Gly 99	-	INSERTION
Gly 100	-	INSERTION
Trp 101	-	INSERTION
Leu 103	Asn 99	CONFLICT
-	Asp 101	DELETION
-	Gly 102	DELETION
-	Tyr 103	DELETION
-	Tyr 104	DELETION
Ser 105	Gly 105	CONFLICT
Asp 107	Ala 107	CONFLICT
Thr 114	Leu 114	CONFLICT
Leu 115	Val 115	CONFLICT
Ser 119	Ala 119	CONFLICT
Thr 128	Tyr 128	CONFLICT
Val 146	Cys 146	CONFLICT

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47183.6
All*	Total formula weight	47183.6

*Water molecules are not included.