1RMF
STRUCTURES OF A MONOCLONAL ANTI-ICAM-1 ANTIBODY R6.5 FRAGMENT AT 2.8 ANGSTROMS RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | IGG2A-KAPPA R6.5 FAB (LIGHT CHAIN) | polymer | 219 | 24068.7 | 1 | PIR (S16112) | Mus musculus (house mouse) | |
| 2 | B (H) | IGG2A-KAPPA R6.5 FAB (HEAVY CHAIN) | polymer | 216 | 23114.9 | 1 | GenBank (2852989) | Mus musculus (house mouse) | |
| 3 | C, D (L, H) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
L: 1 - 219 (PIR: S16112)
H: 2 - 213 (GenBank: 2852989)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Thr 7 | conflict |
| Asn 36 | Thr 36 | conflict |
| His 39 | Tyr 39 | conflict |
| Ser 45 | Pro 45 | conflict |
| Ala 48 | Ser 48 | conflict |
| Leu 51 | Pro 51 | conflict |
| Lys 55 | Arg 55 | conflict |
| Ser 94 | Phe 94 | conflict |
| Ser 96 | Gly 96 | conflict |
| Leu 101 | Tyr 101 | conflict |
| Lys 108 | Arg 108 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 6 | Glu 5 | conflict |
| Ile 30 | Thr 29 | conflict |
| Ala 33 | Pro 32 | conflict |
| Ile 34 | Met 33 | conflict |
| Glu 39 | Gln 38 | conflict |
| Ala 53 | Thr 52 | conflict |
| Ser 55 | Tyr 54 | conflict |
| Asp 57 | Asn 56 | conflict |
| Gln 62 | Arg 61 | conflict |
| Lys 63 | Asn 62 | conflict |
| Asn 77 | Ser 76 | conflict |
| Leu 81 | Met 80 | conflict |
| Gly 99 | - | insertion |
| Gly 100 | - | insertion |
| Trp 101 | - | insertion |
| Leu 103 | Asn 99 | conflict |
| - | Asp 101 | deletion |
| - | Gly 102 | deletion |
| - | Tyr 103 | deletion |
| - | Tyr 104 | deletion |
| Ser 105 | Gly 105 | conflict |
| Asp 107 | Ala 107 | conflict |
| Thr 114 | Leu 114 | conflict |
| Leu 115 | Val 115 | conflict |
| Ser 119 | Ala 119 | conflict |
| Thr 128 | Tyr 128 | conflict |
| Val 146 | Cys 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47183.6 | |
| All* | Total formula weight | 47183.6 |
