1RMF

STRUCTURES OF A MONOCLONAL ANTI-ICAM-1 ANTIBODY R6.5 FRAGMENT AT 2.8 ANGSTROMS RESOLUTION

Functional Information from PDB Data

site_id	CH1
Number of Residues	5
Details	COMPLEMENTARITY DETERMINING REGION FOR HEAVY CHAIN, 1

Chain	Residue
H	ASP31
H	TYR32
H	ALA33
H	ILE34
H	HIS35

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site_id	CH2
Number of Residues	17
Details	COMPLEMENTARITY DETERMINING REGION FOR HEAVY CHAIN, 2

Chain	Residue
H	VAL50
H	ILE51
H	SER52
H	ALA53
H	TYR54
H	SER55
H	GLY56
H	ASP57
H	THR58
H	ASN59
H	TYR60
H	ASN61
H	GLN62
H	LYS63
H	PHE64
H	LYS65
H	GLY66

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site_id	CH3
Number of Residues	10
Details	COMPLEMENTARITY DETERMINING REGION FOR HEAVY CHAIN, 3

Chain	Residue
H	GLY99
H	GLY100
H	TRP101
H	LEU102
H	LEU103
H	LEU104
H	SER105
H	PHE106
H	ASP107
H	TYR108

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site_id	CL1
Number of Residues	16
Details	COMPLEMENTARITY DETERMINING REGION FOR LIGHT CHAIN, 1

Chain	Residue
L	ARG24
L	ASN33
L	GLY34
L	ASN35
L	ASN36
L	TYR37
L	LEU38
L	HIS39
L	SER25
L	SER26
L	GLN27
L	SER28
L	LEU29
L	VAL30
L	HIS31
L	SER32

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site_id	CL2
Number of Residues	7
Details	COMPLEMENTARITY DETERMINING REGION FOR LIGHT CHAIN, 2

Chain	Residue
L	LYS55
L	VAL56
L	SER57
L	ASN58
L	ARG59
L	PHE60
L	SER61

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site_id	CL3
Number of Residues	9
Details	COMPLEMENTARITY DETERMINING REGION FOR LIGHT CHAIN, 3

Chain	Residue
L	SER94
L	GLN95
L	SER96
L	THR97
L	HIS98
L	VAL99
L	PRO100
L	LEU101
L	THR102

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR197-HIS203

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