1RHQ
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A BROMOMETHOXYPHENYL INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Caspase-3 | polymer | 147 | 16639.9 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
| 2 | B, D (B, E) | Caspase-3 | polymer | 102 | 11910.6 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | Cysteine protease CPP32, Yama protein, CPP-32, Apopain, CASP-3, SREBP cleavage activity 1, SCA-1 |
| 3 | E, F (A, D) | 5-S-benzyl-3-({N-[(5-bromo-2-methoxyphenyl)acetyl]-L-valyl}amino)-2,3-dideoxy-5-thio-D-erythro-pentonic acid | non-polymer | 581.5 | 2 | BIRD (PRD_000391) Chemie (0ZZ) |
Sequence modifications
B, E: 310 - 402 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Glu 324 | Asp 190 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57101.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1163.0 | |
| All* | Total formula weight | 58264.0 |
