Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
| E | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 0ZZ A 551 |
| Chain | Residue |
| A | ARG179 |
| B | TRP340 |
| B | ARG341 |
| B | SER381 |
| B | PHE381 |
| A | SER236 |
| A | HIS237 |
| A | GLY238 |
| A | GLU239 |
| A | PHE244 |
| A | CYS285 |
| B | TYR338 |
| B | SER339 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 0ZZ D 551 |
| Chain | Residue |
| D | ARG179 |
| D | SER236 |
| D | HIS237 |
| D | GLY238 |
| D | GLU239 |
| D | PHE244 |
| D | CYS285 |
| E | TYR338 |
| E | SER339 |
| E | TRP340 |
| E | ARG341 |
| E | SER381 |
| E | PHE381 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HskrsSfvCvLLSHG |
| Chain | Residue | Details |
| A | HIS224-GLY238 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKLFIIQACRG |
| Chain | Residue | Details |
| A | LYS276-GLY287 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ARG341 | |
| E | ARG341 | |
| D | HIS237 | |
| D | CYS285 | |
| Chain | Residue | Details |
| A | CYS285 | |
| D | CYS285 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| A | CYS285 | |
| A | HIS237 | |
| A | GLY238 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qx3 |
| Chain | Residue | Details |
| D | CYS285 | |
| D | HIS237 | |
| D | GLY238 | |
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 815 |
| Chain | Residue | Details |
| A | THR177 | electrostatic stabiliser |
| A | SER178 | electrostatic stabiliser |
| A | HIS237 | electrostatic stabiliser, proton acceptor, proton donor |
| A | GLY238 | electrostatic stabiliser |
| A | CYS285 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 815 |
| Chain | Residue | Details |
| D | THR177 | electrostatic stabiliser |
| D | SER178 | electrostatic stabiliser |
| D | HIS237 | electrostatic stabiliser, proton acceptor, proton donor |
| D | GLY238 | electrostatic stabiliser |
| D | CYS285 | electrostatic stabiliser |
