1RF7
STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDROFOLATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DIHYDROFOLATE REDUCTASE | polymer | 159 | 18020.3 | 1 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli | DHFR |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | A | DIHYDROFOLIC ACID | non-polymer | 443.4 | 2 | Chemie (DHF) | |||
| 5 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
| PDB | External Database | Details |
|---|---|---|
| Asp 37 | Asn 37 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18020.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 977.2 | |
| All* | Total formula weight | 18997.5 |
