1R9O
Crystal Structure of P4502C9 with Flurbiprofen bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 2C9 | polymer | 477 | 54322.9 | 1 | UniProt (P11712) Pfam (PF00067) | Homo sapiens (human) | CYPIIC9, P450 PB-1, P450 MP-4, S-mephenytoin 4-hydroxylase, P-450MP |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | FLURBIPROFEN | non-polymer | 244.3 | 1 | Chemie (FLP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A: 23 - 490 (UniProt: P11712)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | engineered mutation |
| Ala 19 | - | engineered mutation |
| Lys 20 | - | engineered mutation |
| Lys 21 | - | engineered mutation |
| Thr 22 | - | engineered mutation |
| Ile 490 | Val 490 | engineered mutation |
| His 491 | - | expression tag |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54322.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 952.8 | |
| All* | Total formula weight | 55275.7 |
