1R6A
Structure of the dengue virus 2'O methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Genome polyprotein | polymer | 295 | 33145.7 | 1 | UniProt (P12823) Pfam (PF01728) In PDB | Dengue virus 2 Puerto Rico/PR159-S1/1969 | NS5 |
2 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
3 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
4 | A | RIBAVIRIN MONOPHOSPHATE | non-polymer | 324.2 | 1 | Chemie (RVP) | |||
5 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 4 - 296 (UniProt: P12823)
PDB | External Database | Details |
---|---|---|
Gly 2 | - | cloning artifact |
Ser 3 | - | cloning artifact |
Ile 135 | Val 2623 | conflict |
Arg 139 | Lys 2627 | conflict |
Ser 173 | Asn 2661 | conflict |
Lys 193 | Arg 2681 | conflict |
Ala 196 | Thr 2684 | conflict |
His 201 | Tyr 2689 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33145.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1381.0 | |
All* | Total formula weight | 34526.7 |