1R64
The 2.2 A crystal structure of Kex2 protease in complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kexin | polymer | 481 | 52640.0 | 2 | UniProt (P13134) Pfam (PF00082) Pfam (PF01483) | Saccharomyces cerevisiae (baker's yeast) | KEX2 protease, Proteinase YSCF |
| 2 | C, D (C, D) | Ac-Arg-Glu-Lys-boroArg peptide inhibitor | polymer | 5 | 615.5 | 2 | BIRD (PRD_000420) | ||
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H, O (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | I, J, K, P, Q... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 6 | L, M, N, S, T... (A, B) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 7 | V (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 8 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 769 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106511.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1347.9 | |
| All* | Total formula weight | 108707.8 |
