1R5K
Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Estrogen receptor | polymer | 261 | 29850.2 | 3 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, Estradiol receptor, ER-alpha |
2 | A, B, C | (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID | non-polymer | 354.4 | 3 | Chemie (GW5) | |||
3 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B, C: 297 - 554 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
Met 294 | - | cloning artifact |
Asp 295 | - | cloning artifact |
Pro 296 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 89550.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1063.3 | |
All* | Total formula weight | 90614.0 |