1R5K
Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Estrogen receptor | polymer | 261 | 29850.2 | 3 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | ER, Estradiol receptor, ER-alpha |
| 2 | D, E, F (A, B, C) | (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID | non-polymer | 354.4 | 3 | Chemie (GW5) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B, C: 297 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Met 294 | - | cloning artifact |
| Asp 295 | - | cloning artifact |
| Pro 296 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89550.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1063.3 | |
| All* | Total formula weight | 90614.0 |
