1R1H
STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neprilysin | polymer | 696 | 79525.5 | 1 | UniProt (P08473) Pfam (PF05649) Pfam (PF01431) | Homo sapiens (human) | Neutral endopeptidase, NEP, Enkephalinase, Common acute lymphocytic leukemia antigen, CALLA, Neutral endopeptidase 24.11, CD10 |
| 2 | B, C, D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 3 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | F (A) | N-[3-[(1-AMINOETHYL)(HYDROXY)PHOSPHORYL]-2-(1,1'-BIPHENYL-4-YLMETHYL)PROPANOYL]ALANINE | non-polymer | 418.4 | 1 | Chemie (BIR) | |||
| 5 | G (A) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79525.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1147.5 | |
| All* | Total formula weight | 80673.0 |
