1QZF
Crystal structure of DHFR-TS from Cryptosporidium hominis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 521 | 60262.5 | 5 | UniProt (Q27552) Pfam (PF00186) Pfam (PF00303) | Cryptosporidium hominis | |
| 2 | F, J, N, R, V (A, B, C, D, E) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 5 | Chemie (UMP) | |||
| 3 | G, K, O, S, W (A, B, C, D, E) | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 5 | Chemie (CB3) | |||
| 4 | H, L, P, T, X (A, B, C, D, E) | FOLIC ACID | non-polymer | 441.4 | 5 | Chemie (FOL) | |||
| 5 | I, M, Q, U, Y (A, B, C, D, E) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 5 | Chemie (NDP) | |||
| 6 | AA, BA, CA, DA, Z (B, C, D, E, A) | water | water | 18.0 | 406 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 301312.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 9862.3 | |
| All* | Total formula weight | 311174.9 |
