1QXE
Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin alpha chain | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Hemoglobin beta chain | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | |
| 3 | E, I, J, M, Q... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | F, K, N, T (A, B, C, D) | OXYGEN MOLECULE | non-polymer | 32.0 | 4 | Chemie (OXY) | |||
| 5 | G, L, O, U (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 6 | H, P (A, C) | 5-HYDROXYMETHYL-FURFURAL | non-polymer | 126.1 | 2 | Chemie (FUX) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 537 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3518.6 | |
| All* | Total formula weight | 65599.7 |
