1QW7
Structure of an Engineered Organophosphorous Hydrolase with Increased Activity Toward Hydrolysis of Phosphothiolate Bonds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Parathion hydrolase | polymer | 336 | 36394.4 | 2 | UniProt (P0A434) Pfam (PF02126) In PDB | Brevundimonas diminuta | Phosphotriesterase, PTE |
| 2 | A, B | COBALT (II) ION | non-polymer | 58.9 | 4 | Chemie (CO) | |||
| 3 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | A, B | DIETHYL 4-METHYLBENZYLPHOSPHONATE | non-polymer | 242.3 | 2 | Chemie (EBP) | |||
| 5 | water | water | 18.0 | 525 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 365 (UniProt: P0A434)
| PDB | External Database | Details |
|---|---|---|
| Arg 254 | His 254 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72788.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 766.2 | |
| All* | Total formula weight | 73555.1 |
