1QVN
Structure of SP4160 Bound to IL-2 V69A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-2 | polymer | 132 | 15306.8 | 4 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-cell growth factor, TCGF, Aldesleukin |
| 2 | E, G, H, J (A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, I, K, L (A, B, C, D) | 2-GUANIDINO-4-METHYL-PENTANOIC ACID [2-(4-{5-[4-(4-ACETYLAMINO-BENZYLOXY)-2,3-DICHLORO-PHENYL]-2-METHYL-2H-PYRAZOL-3-YL}-PIPERIDIN-1-YL)-2-OXO-ETHYL]-AMIDE | non-polymer | 685.6 | 4 | Chemie (FRI) |
Sequence modifications
A, B, C, D: 1 - 132 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Ala 69 | Val 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61227.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3004.2 | |
| All* | Total formula weight | 64231.5 |
