1QR3
Structure of porcine pancreatic elastase in complex with FR901277, a novel macrocyclic inhibitor of elastases at 1.6 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Chymotrypsin-like elastase family member 1 | polymer | 240 | 25928.0 | 1 | UniProt (P00772) Pfam (PF00089) | Sus scrofa (Pig) | Elastase-1 |
| 2 | B (I) | FR901277 Inhibitor | polymer | 8 | 1016.1 | 1 | BIRD (PRD_000561) | Streptomyces resistomycificus | |
| 3 | C (E) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (E) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (E, I) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
E: 16 - 245 (UniProt: P00772)
| PDB | External Database | Details |
|---|---|---|
| Asn 77 | Asp 92 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26944.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 136.1 | |
| All* | Total formula weight | 27080.3 |
